Can Tribble 3 Can Induce Non-Alcoholic Fatty Liver Disease?
Can Tribble 3 Can Induce Non-Alcoholic Fatty Liver Disease?
Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. Recent research has found that the expression of hepatic TRB3 increased in a rat model of diabetes. TRB3 could block the insulin signaling pathway through inhibiting Akt activation, which contributes to insulin resistance. This research, lead by Dr.